About Panorama
The study is divided into five periods, lasting five years in total, as described below.
Panorama Study Outline
Screening: After informed consent, the study doctor will confirm that the recipient and donor can enter the study.
Conditioning: Starting about 10 days before transplant, a combination of experimental drugs and treatments, including siplizumab, will be given.
Kidney transplantation: The kidney transplant and donor bone marrow infusion will be performed and the standard anti-rejection drugs started.
Post-transplant weaning: If the recipient and kidney are doing well the anti-rejection drugs may be gradually reduced with the goal of stopping by about one year after transplant.
Follow-up: The main study assessment will be at two years with further follow-up until 5 years post-transplant.
Where can I find more information on kidney transplantation?
A general background to kidney transplantation is provided by the National Kidney Foundation. Click the link below to visit their website:
www.kidney.org